Scope & Invitation
Investigating the behavior of hierarchically composed systems is a challenging task, owing to a cascade of various, interrelated intricacies across several orders of magnitude, including physical properties, morphological configurations, as well as the development of the material over time. This is true for a broad range of biological systems, and particularly relevant for the fields of biomechanics and mechanobiology. Biomechanics deals with quantifying the effects of mechanical forces on biological systems (such as the musculoskeletal system, or specific parts thereof, or the fluids contained in pore spaces), hence providing insights as to the correspondingly arising mechanical stresses and strains. In hierarchically organized biological systems, stresses and strains vary, potentially to a significant extent, between the different observation scales involved. The latter range from the scales of whole organs down to the scale of single molecules. The emerging field of mechanobiology, in turn, attempts to understand how cells or other biological factors (such as proteins, hormones, or growth factors) respond to their mechanical environments, and how these responses affect the overall biological system; thereby bridging the fundamentally different, but yet complementary fields of engineering mechanics, on the one hand, and genetics and molecular biology, on the other hand.
The MultiBioMe 2017 is the inaugural edition of a new, biennial series of scientific gatherings, offering a platform for presenting and discussing the latest advances and developments in the thriving fields of biomechanics and mechanobiology. In particular, the focus of this conference lies on reconciliation of the distinct spatial and time scales at which related processes and mechanisms occur, considering for that purpose the whole range of available techniques, including experimentation, imaging and visualization, mathematical modelling, as well as numerical simulation. Emphasis will be on multidisciplinary scientific approaches genuinely taking into account the inherent multiscale nature of the studied biomechanical and mechanobiological phenomena, and demonstrating successful synergies between the involved disciplines. Studies relating to all kinds of biological systems are welcome, including hard tissues, soft tissues, and tissue engineering applications, ranging from the molecular to the structural level.